11017917 (CellType: myocyte) IP3 releases Ca2+ from intracellular stores by opening specific Ca2+ channels (IP3R).
12621039 (Organ: cerebellar, CellType: Brain Stem, CellLineName: ng108-15) It has been reported that IP3 binding to the IP3R is not cooperative ( 31 , 33 ), and the same property holds true for the wild-type receptor and all of the mutant receptors except D1-223 expressed in R23-11 cells (Table I ).