11181532 PKA is known to phosphorylate and increase the transcriptional activity of several closely related transcription factors in the bZIP family, namely cAMP response element binding protein (CREB), cAMP response element modulator (CREM), and activating transcription factor-1 (ATF-1) (reviewed in Ref. 63 ).
17464208 (CellType: macrophage, CellLineName: RAW264.7) These results indicate that PKA phosphorylates CREB and so induces VEGF gene expression.