• http://rdf.wikipathways.org/Pathway/WP3282_r117615/Comment/6bfe55918786bf446ca3911f7138e453
  • http://www.w3.org/1999/02/22-rdf-syntax-ns#type
    • http://vocabularies.wikipathways.org/gpml#Comment
  • http://purl.org/dc/terms/isPartOf
    • http://rdf.wikipathways.org/Pathway/WP3282_r117615/DataNode/f2340
  • http://vocabularies.wikipathways.org/gpml#commentText
    • P13K converts membrane lipid PIP2 to PIP3 by adding a phosphate. P13K activity is dependent upon CD28 co-stimulation because P13K can bind to phosphorylated ITIMs on CD28. PI3K can also bind ICOS
• http://rdf.wikipathways.org/Pathway/WP3282_r117615/DataNode/f2340
  • http://vocabularies.wikipathways.org/gpml#hasComment
    • http://rdf.wikipathways.org/Pathway/WP3282_r117615/Comment/6bfe55918786bf446ca3911f7138e453