PLC-g is a phospholipase, a class of enzymes that cleave phospholipids just before the phosphate group.
PLC-g is initially brought to the plasma membrane by binding of its PH domain to membrane lipid PIP3. PLC-g then binds to LAT and SLP-76 and can be activated by Itk mediated phosphorylation.
PLC-g ultimately produces 3 different second messangers to activate 3 paths leading to different TFs that lead to IL-2 transcription