extrafollicular IgM-secreting plasmablast-
Successful migration of plasmablasts to their site of extrafollicular growth is partially influenced by the downregulation of CXCR5 and CCR7, which decreases their responsiveness to follicular and T-zone chemokines (CXCL13, CCL19, and
CCL21).
Plasmablasts are suspected to be direct actors in SARS-CoV-2 pathologgy.