Recently, we have described a new
role for paxillin in regulating MT stability, via interaction with and inhibition of the cytoplasmic deacetylase HDAC6, that in turn controls Golgi organization and directed cell migration
Interestingly, the focal adhesion scaffold protein Paxillin interacts with HDAC6 and inhibits its deacetylase activity to upregulate microtubule acetylation during cell invasion