Previous studies have documented several proteins as the substrates of HDAC6, including α-tubulin (Hubbert et al., 2002; Zhang et al., 2003), Hsp90 (Kovacs et al., 2005), cortactin (Zhang et al., 2007), peroxiredoxins (Parmigiani et al., 2008), β-catenin (Li et al., 2008), Ku70 (Subramanian et al., 2011), Tat (Huo et al., 2011), and survivin (Riolo et al., 2012).
Note:SURVIVIN is an alias for BIRC5.