HDAC6 modulates cell motility by altering the acetylation level of cortactin.
[from the second reference]This suggests that HDAC6 promotes dendritic growth and Golgi polarization through cortactin deacetylation in vitro.
Taken together, this study suggests that HDAC6 and SIRT2 regulate neuronal migration and dendrite development through cortactin deacetylation in vivo