15814901 Later, Xie and Rothstein showed that PKC phosphorylates CREB on Ser133 in B cells [ 41 ].
15262987 In favor of this possibility, CREB has been shown to be phosphorylated by PKC in vitro ( 16 ).
11591753 Several pieces of evidence suggest that PKC can phosphorylate CREB directly.
11574420 Phosphorylation of CREB by PKC was reported to increase the binding of CREB to CRE in vitro and to stimulate CREB homodimerization or heterodimer complex formation with ATF-1, a transcription factor that shares many structural properties with CREB ( 37 , 38 , 39 , 40 ).