14988405 The 5-hydroxytryptamine type 2A (5-HT(2A)) receptor and the 5-HT(2C) receptor are closely related members of the G-protein-coupled receptors activated by serotonin that share very similar pharmacological profiles and cellular signaling pathways.
8626761 (CellLineName: 3T3) In related experiments with cells that stably overexpress 5-HT2aR, serotonin also increased PI turnover as well as the secretion of APPs, indicating that DNF is a nonselective agonist of both 5-HT2aR and 5-HT2cR (data not shown).