SPARQL | HTML5 RDFa and Microdata document
https://identifiers.org/pubmed/11040209 https://identifiers.org/pubmed/9585500 https://identifiers.org/ensembl/ENSBTAG00000000696 https://identifiers.org/ensembl/ENSBTAG00000009566 https://identifiers.org/ensembl/ENSBTAG00000000504 https://identifiers.org/ensembl/ENSBTAG00000001856 https://identifiers.org/ensembl/ENSBTAG00000002072 https://identifiers.org/ensembl/ENSBTAG00000002545 https://identifiers.org/ensembl/ENSBTAG00000004781 https://identifiers.org/ensembl/ENSBTAG00000004820 https://identifiers.org/ensembl/ENSBTAG00000005160 https://identifiers.org/ensembl/ENSBTAG00000005311 https://identifiers.org/ensembl/ENSBTAG00000006481 https://identifiers.org/ensembl/ENSBTAG00000007270 https://identifiers.org/ensembl/ENSBTAG00000008642 https://identifiers.org/ensembl/ENSBTAG00000009483 https://identifiers.org/ensembl/ENSBTAG00000009709 https://identifiers.org/ensembl/ENSBTAG00000010036 https://identifiers.org/ensembl/ENSBTAG00000010298 https://identifiers.org/ensembl/ENSBTAG00000011046 https://identifiers.org/ensembl/ENSBTAG00000011945 https://identifiers.org/ensembl/ENSBTAG00000012243 https://identifiers.org/ensembl/ENSBTAG00000012691 https://identifiers.org/ensembl/ENSBTAG00000014166 https://identifiers.org/ensembl/ENSBTAG00000015002 https://identifiers.org/ensembl/ENSBTAG00000016848 https://identifiers.org/ensembl/ENSBTAG00000018044 https://identifiers.org/ensembl/ENSBTAG00000019366 https://identifiers.org/ensembl/ENSBTAG00000019803 https://identifiers.org/ensembl/ENSBTAG00000020776 https://identifiers.org/ensembl/ENSBTAG00000020777 https://identifiers.org/ensembl/ENSBTAG00000022539 https://identifiers.org/ensembl/ENSBTAG00000026660 https://identifiers.org/ensembl/ENSBTAG00000027983 https://identifiers.org/ensembl/ENSBTAG00000030801 https://identifiers.org/ensembl/ENSBTAG00000030966 https://identifiers.org/ensembl/ENSBTAG00000031656 https://identifiers.org/ensembl/ENSBTAG00000034495 https://identifiers.org/ensembl/ENSBTAG00000040199 https://identifiers.org/ensembl/ENSBTAG00000046192 https://identifiers.org/ensembl/ENSBTAG00000046757 https://identifiers.org/ensembl/ENSBTAG00000046765 https://identifiers.org/wikipathways/WP1066 http://rdf.wikipathways.org/Pathway/WP1066_r136951/WP/Interaction/a1216 http://rdf.wikipathways.org/Pathway/WP1066_r136951/WP/Interaction/a690f http://rdf.wikipathways.org/Pathway/WP1066_r136951/WP/Interaction/a9f73 http://rdf.wikipathways.org/Pathway/WP1066_r136951/WP/Interaction/b1c3d http://rdf.wikipathways.org/Pathway/WP1066_r136951/WP/Interaction/b29a0 http://rdf.wikipathways.org/Pathway/WP1066_r136951/WP/Interaction/b8bb3 http://rdf.wikipathways.org/Pathway/WP1066_r136951/WP/Interaction/bc2ce http://rdf.wikipathways.org/Pathway/WP1066_r136951/WP/Interaction/c1382 http://rdf.wikipathways.org/Pathway/WP1066_r136951/WP/Interaction/c4c40 http://rdf.wikipathways.org/Pathway/WP1066_r136951/WP/Interaction/c6c8c http://rdf.wikipathways.org/Pathway/WP1066_r136951/WP/Interaction/ca478 http://rdf.wikipathways.org/Pathway/WP1066_r136951/WP/Interaction/ce5c0 http://rdf.wikipathways.org/Pathway/WP1066_r136951/WP/Interaction/ceaf3 http://rdf.wikipathways.org/Pathway/WP1066_r136951/WP/Interaction/cedb4 http://rdf.wikipathways.org/Pathway/WP1066_r136951/WP/Interaction/d0fea http://rdf.wikipathways.org/Pathway/WP1066_r136951/WP/Interaction/d18f3 http://rdf.wikipathways.org/Pathway/WP1066_r136951/WP/Interaction/d4f51 http://rdf.wikipathways.org/Pathway/WP1066_r136951/WP/Interaction/d6308 http://rdf.wikipathways.org/Pathway/WP1066_r136951/WP/Interaction/d7fc6 http://rdf.wikipathways.org/Pathway/WP1066_r136951/WP/Interaction/dafbc http://rdf.wikipathways.org/Pathway/WP1066_r136951/WP/Interaction/dc889 http://rdf.wikipathways.org/Pathway/WP1066_r136951/WP/Interaction/dd463 http://rdf.wikipathways.org/Pathway/WP1066_r136951/WP/Interaction/de9ae http://rdf.wikipathways.org/Pathway/WP1066_r136951/WP/Interaction/e71e5 http://rdf.wikipathways.org/Pathway/WP1066_r136951/WP/Interaction/ea89e http://rdf.wikipathways.org/Pathway/WP1066_r136951/WP/Interaction/ebbe3 http://rdf.wikipathways.org/Pathway/WP1066_r136951/WP/Interaction/f4a0a http://rdf.wikipathways.org/Pathway/WP1066_r136951/WP/Interaction/f525a http://rdf.wikipathways.org/Pathway/WP1066_r136951/WP/Interaction/f6ea6 http://rdf.wikipathways.org/Pathway/WP1066_r136951/WP/Interaction/f9082 http://rdf.wikipathways.org/Pathway/WP1066_r136951/WP/Interaction/ff5b9 https://identifiers.org/wikipathways/WP1066_r136951
http://www.w3.org/1999/02/22-rdf-syntax-ns#type
http://vocabularies.wikipathways.org/wp#Pathway
http://www.w3.org/2004/02/skos/core#Collection
http://xmlns.com/foaf/0.1/page
http://www.wikipathways.org/instance/WP1066_r136951
http://purl.org/dc/elements/1.1/identifier
https://identifiers.org/wikipathways/WP1066
http://purl.org/dc/elements/1.1/source http://purl.org/dc/elements/1.1/title
Eukaryotic transcription initiation
http://purl.org/dc/terms/description
In eukaryotes, RNA polymerase, and therefore the initiation of transcription, requires the presence of a core promoter sequence in the DNA. RNA polymerase is able to bind to core promoters in the presence of various specific transcription factors. The most common type of core promoter in eukaryotes is a short DNA sequence known as a TATA box. The TATA box, as a core promoter, is the binding site for a transcription factor known as TATA binding protein (TBP), which is itself a subunit of another transcription factor, called Transcription Factor II D (TFIID). After TFIID binds to the TATA box via the TBP, five more transcription factors and RNA polymerase combine around the TATA box in a series of stages to form a preinitiation complex. One transcription factor, DNA helicase, has helicase activity and so is involved in the separating of opposing strands of double-stranded DNA to provide access to a single-stranded DNA template. However, only a low, or basal, rate of transcription is driven by the preinitiation complex alone. Other proteins known as activators and repressors, along with any associated coactivators or corepressors, are responsible for modulating transcription rate.
Source: [Wikipedia](https://en.wikipedia.org/wiki/Transcription_(biology))
http://purl.org/dc/terms/identifier http://purl.org/dc/terms/references
https://identifiers.org/pubmed/9585500
https://identifiers.org/pubmed/11040209
http://purl.org/spar/cito/cites
https://identifiers.org/pubmed/9585500
https://identifiers.org/pubmed/11040209
http://vocabularies.wikipathways.org/wp#isAbout
http://rdf.wikipathways.org/Pathway/WP1066_r136951
http://vocabularies.wikipathways.org/wp#ontologyTag
http://purl.obolibrary.org/obo/PW_0001274
http://purl.obolibrary.org/obo/PW_0001570
http://purl.obolibrary.org/obo/PW_0001575
http://vocabularies.wikipathways.org/wp#Curation:AnalysisCollection
http://vocabularies.wikipathways.org/wp#Curation:Homology_Converted
http://vocabularies.wikipathways.org/wp#organism
http://purl.obolibrary.org/obo/NCBITaxon_9913
http://vocabularies.wikipathways.org/wp#organismName http://vocabularies.wikipathways.org/wp#pathwayOntologyTag
http://purl.obolibrary.org/obo/PW_0001274
http://purl.obolibrary.org/obo/PW_0001570
http://purl.obolibrary.org/obo/PW_0001575
http://xmlns.com/foaf/0.1/img
https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP1066&oldid=136951
https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP1066&oldid=136951