SPARQL | HTML5 RDFa and Microdata document 
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      http://www.w3.org/1999/02/22-rdf-syntax-ns#type   
          http://www.w3.org/2004/02/skos/core#Collection 
          http://vocabularies.wikipathways.org/wp#Pathway 
         http://vocabularies.wikipathways.org/wp#isAbout   
          http://rdf.wikipathways.org/Pathway/WP1154_r122865 
         http://vocabularies.wikipathways.org/wp#ontologyTag   
          http://vocabularies.wikipathways.org/wp#Curation:Homology_Converted 
          http://purl.obolibrary.org/obo/PW_0000198 
          http://vocabularies.wikipathways.org/wp#Curation:AnalysisCollection 
         http://vocabularies.wikipathways.org/wp#organism   
          http://purl.obolibrary.org/obo/NCBITaxon_9615 
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          http://purl.obolibrary.org/obo/PW_0000198 
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          http://www.wikipathways.org/instance/WP1154_r122865 
         http://purl.org/dc/elements/1.1/identifier   
          https://identifiers.org/wikipathways/WP1154 
         http://purl.org/dc/elements/1.1/source   http://purl.org/dc/elements/1.1/title   
          p38 MAPK signaling pathway 
         http://purl.org/dc/terms/description   
          p38 MAPKs are members of the MAPK family that are activated by a variety of environmental stresses and inflammatory cytokines. Stress signals are delivered to this cascade by members of small GTPases of the Rho family (Rac, Rho, Cdc42). As with other MAPK cascades, the membrane-proximal component is a MAPKKK, typically a MEKK or a mixed lineage kinase (MLK). The MAPKKK phosphorylates and activated MKK3/5, the p38 MAPK kinase. MKK3/6 can also be activated directly by ASK1, which is stimulated by apoptotic stimuli. P38 MAK is involved in regulation of Hsp27 and MAPKAP-2 and several transcription factors including ATF2, STAT1, THE Max/Myc complex, MEF-2, ELK-1 and indirectly CREB via activation of MSK1. 
         http://purl.org/dc/terms/identifier   http://purl.org/dc/terms/references   
          https://identifiers.org/pubmed/10487205 
          https://identifiers.org/pubmed/10498912 
          https://identifiers.org/pubmed/10527909 
          https://identifiers.org/pubmed/10557099 
          https://identifiers.org/pubmed/11163208 
          https://identifiers.org/pubmed/10067858 
          https://identifiers.org/pubmed/10097111 
          https://identifiers.org/pubmed/10207619 
         http://purl.org/spar/cito/cites   
          https://identifiers.org/pubmed/10067858 
          https://identifiers.org/pubmed/10097111 
          https://identifiers.org/pubmed/10207619 
          https://identifiers.org/pubmed/11163208 
          https://identifiers.org/pubmed/10527909 
          https://identifiers.org/pubmed/10557099 
          https://identifiers.org/pubmed/10487205 
          https://identifiers.org/pubmed/10498912