Pathways in physiological and pathological hypertrophy of the heart. Largely based on the article from [https://www.ncbi.nlm.nih.gov/pubmed/11714087 Wang et al, 'Signal transduction in cardiac hypertrophy--dissecting compensatory versus pathological pathways utilizing a transgenic approach.]
Hypertrohpy of the heart can be a physiological compensation for exercise, but it can also be a pathological compensation for hypertension and stress.
Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP1528 CPTAC Assay Portal]