The most frequently altered genes in glioblastoma. This pathway originally accompanied the 2008 Nature publication on the comprehensive genomic characterization of human glioblastoma genes and core pathways by TCGA, The Cancer Genome Atlas (see Bibliography). Assembled from literature and public pathway database resources, this representation can easily be kept up to date at WikiPathways.org.
Sources: [cBio Cancer Genomics Portal](http://cbio.mskcc.org/cancergenomics/gbm/pathways/GBM_pathway_20080708.pdf)
Proteins on this pathway have targeted assays available via the [CPTAC Assay Portal](https://assays.cancer.gov/available_assays?wp_id=WP2261)