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http://rdf.wikipathways.org/Pathway/WP2882_r126680/WP/Interaction/idd3f66ad8 http://rdf.wikipathways.org/Pathway/WP2882_r126680/WP/Interaction/idd51964a8 http://rdf.wikipathways.org/Pathway/WP2882_r126680/WP/Interaction/ide30920ff http://rdf.wikipathways.org/Pathway/WP2882_r126680/WP/Interaction/ide426961c http://rdf.wikipathways.org/Pathway/WP2882_r126680/WP/Interaction/ide672e3c1 http://rdf.wikipathways.org/Pathway/WP2882_r126680/WP/Interaction/idf13776e http://rdf.wikipathways.org/Pathway/WP2882_r126680/WP/Interaction/idff97ba66 https://identifiers.org/wikipathways/WP2882_r126680
http://www.w3.org/1999/02/22-rdf-syntax-ns#type
http://vocabularies.wikipathways.org/wp#Pathway
http://www.w3.org/2004/02/skos/core#Collection
http://vocabularies.wikipathways.org/wp#isAbout
http://rdf.wikipathways.org/Pathway/WP2882_r126680
http://vocabularies.wikipathways.org/wp#ontologyTag
http://purl.obolibrary.org/obo/PW_0000716
http://purl.obolibrary.org/obo/PW_0000004
http://vocabularies.wikipathways.org/wp#Curation:AnalysisCollection
http://vocabularies.wikipathways.org/wp#Curation:ONTOX
http://vocabularies.wikipathways.org/wp#organism
http://purl.obolibrary.org/obo/NCBITaxon_9606
http://vocabularies.wikipathways.org/wp#organismName http://vocabularies.wikipathways.org/wp#pathwayOntologyTag
http://purl.obolibrary.org/obo/PW_0000716
http://purl.obolibrary.org/obo/PW_0000004
http://xmlns.com/foaf/0.1/img
https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP2882&oldid=126680
https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP2882&oldid=126680
http://xmlns.com/foaf/0.1/page
http://www.wikipathways.org/instance/WP2882_r126680
http://purl.org/dc/elements/1.1/identifier
https://identifiers.org/wikipathways/WP2882
http://purl.org/dc/elements/1.1/source http://purl.org/dc/elements/1.1/title
Nuclear receptors meta-pathway
http://purl.org/dc/terms/description
In the field of molecular biology, nuclear receptors are a class of proteins found within cells that are responsible for sensing steroid and thyroid hormones and certain other molecules. In response, these receptors work with other proteins to regulate the expression of specific genes, thereby controlling the development, homeostasis, and metabolism of the organism.
Nuclear receptors have the ability to directly bind to DNA and regulate the expression of adjacent genes, hence these receptors are classified as transcription factors. The regulation of gene expression by nuclear receptors generally only happens when a ligand is present. More specifically, ligand binding to a nuclear receptor results in a conformational change in the receptor, which, in turn, activates the receptor, resulting in up- or down-regulation of gene expression.
A unique property of nuclear receptors that differentiates them from other classes of receptors is their ability to directly interact with and control the expression of genomic DNA. As a consequence, nuclear receptors play key roles in both embryonic development and adult homeostasis. Nuclear receptors may be classified according to either mechanism or homology.
[From Wikipedia, the free encyclopedia]
http://purl.org/dc/terms/identifier http://purl.org/dc/terms/references
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