SPARQL | HTML5 RDFa and Microdata document
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    • http://purl.org/dc/terms/isPartOf
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    • http://www.w3.org/1999/02/22-rdf-syntax-ns#type
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      • http://purl.obolibrary.org/obo/PW_0000095
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      • http://purl.obolibrary.org/obo/NCBITaxon_10116
    • http://vocabularies.wikipathways.org/wp#organismName
      • Rattus norvegicus
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      • http://purl.obolibrary.org/obo/PW_0000095
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      • WikiPathways
    • http://purl.org/dc/elements/1.1/title
      • G1 to S cell cycle control
    • http://purl.org/dc/terms/description
      • In the G1 phase there are two types of DNA damage responses, the p53-dependent and the p53-independent pathways. The p53-dependent responses inhibit CDKs through the up-regulation of genes encoding CKIs mediated by the p53 protein, whereas the p53-independent mechanisms inhibit CDKs through the inhibitory T14Y15 phosphorylation of Cdk2. Failure of DNA damage checkpoints in G1 leads to mutagenic replication of damaged templates and other replication defects. Source: Reactome http://www.reactome.org/cgi-bin/eventbrowser?DB=gk_current&FOCUS_SPECIES=Homo%20sapiens&ID=69615&
    • http://purl.org/dc/terms/identifier
      • WP348
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      • https://identifiers.org/pubmed/12164919
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      • https://identifiers.org/pubmed/12164919