The production of fatty acids from acetyl-CoA and NADPH through the use of enzymes known as fatty acid synthases is referred to as fatty acid synthesis. This biological process occurs within the cytoplasm of cells. The majority of acetyl-CoA that is transformed into fatty acids originates from carbohydrates through the glycolytic pathway.
Proteins on this pathway have targeted assays available via the [CPTAC Assay Portal](https://assays.cancer.gov/available_assays?wp_id=WP357).