SPARQL | HTML5 RDFa and Microdata document
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http://purl.org/dc/elements/1.1/source http://purl.org/dc/elements/1.1/title
MAPK and NFkB signaling inhibited by Yersinia YopJ
http://purl.org/dc/terms/description
This pathway is based on the figure 24.1 of "In Vitro Signaling by MAPK and NFκB Pathways Inhibited by Yersinia YopJ" (see bibliography). In the MAPK and NFkB pathways, YopJ is the main inhibitor of Raf and TRAF6, NIK, or MEKK1. YopJ, in the NFkB pathway, may inhibit TRAF6,NIK, or MEKK. The pathway is activated by the stimulus of the genes TRAF6, NIK, or MEKK1, or the stimulus on the interactions between Ras to Raf. In the NFkB pathway along with the MAPK pathway, with the use of activators such as kinases, G-proteins, and E3 ligases, are catalysts to initiate of signaling cascades with a concentrated lysate.
Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP3849 CPTAC Assay Portal]
http://purl.org/dc/terms/identifier http://purl.org/dc/terms/references
https://identifiers.org/pubmed/18413260
http://purl.org/spar/cito/cites
https://identifiers.org/pubmed/18413260