SPARQL | HTML5 RDFa and Microdata document
https://identifiers.org/uniprot/Q99558 https://identifiers.org/ensembl/ENSG00000175104 https://identifiers.org/uniprot/Q13233 https://identifiers.org/ensembl/ENSG00000100030 https://identifiers.org/ensembl/ENSG00000104365 https://identifiers.org/ensembl/ENSG00000109320 https://identifiers.org/ensembl/ENSG00000126458 https://identifiers.org/ensembl/ENSG00000132155 https://identifiers.org/ensembl/ENSG00000213341 https://identifiers.org/ensembl/ENSG00000269335 https://identifiers.org/uniprot/P25963 https://identifiers.org/uniprot/P52564 https://identifiers.org/pubmed/18413260 https://identifiers.org/wikipathways/WP3849 http://rdf.wikipathways.org/Pathway/WP3849_r137216/Complex/a3d51 http://rdf.wikipathways.org/Pathway/WP3849_r137216/Complex/b2fcc http://rdf.wikipathways.org/Pathway/WP3849_r137216/ComplexBinding/a3d51 http://rdf.wikipathways.org/Pathway/WP3849_r137216/ComplexBinding/b2fcc http://rdf.wikipathways.org/Pathway/WP3849_r137216/WP/Interaction/id1b03f1f2 http://rdf.wikipathways.org/Pathway/WP3849_r137216/WP/Interaction/id92ed2801 http://rdf.wikipathways.org/Pathway/WP3849_r137216/WP/Interaction/idc8386b59 http://rdf.wikipathways.org/Pathway/WP3849_r137216/WP/Interaction/idcb718969 https://identifiers.org/wikipathways/WP3849_r137216
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http://purl.obolibrary.org/obo/PW_0000007
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https://identifiers.org/wikipathways/WP3849
http://purl.org/dc/elements/1.1/source http://purl.org/dc/elements/1.1/title
MAPK and NFkB signaling inhibited by Yersinia YopJ
http://purl.org/dc/terms/description
This pathway is based on the figure 24.1 of "In Vitro Signaling by MAPK and NFκB Pathways Inhibited by Yersinia YopJ" (see bibliography). In the MAPK and NFkB pathways, YopJ is the main inhibitor of Raf and TRAF6, NIK, or MEKK1. YopJ, in the NFkB pathway, may inhibit TRAF6, NIK, or MEKK. The pathway is activated by the stimulus of the genes TRAF6, NIK, or MEKK1, or the stimulus on the interactions between Ras to Raf. In the NFkB pathway along with the MAPK pathway, with the use of activators such as kinases, G-proteins, and E3 ligases, are catalysts to initiate of signaling cascades with a concentrated lysate.
Proteins on this pathway have targeted assays available via the [CPTAC Assay Portal](https://assays.cancer.gov/available_assays?wp_id=WP3849)
http://purl.org/dc/terms/identifier http://purl.org/dc/terms/references
https://identifiers.org/pubmed/18413260
http://purl.org/spar/cito/cites
https://identifiers.org/pubmed/18413260