SPARQL | HTML5 RDFa and Microdata document
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      • https://identifiers.org/wikipathways/WP3932_r137139
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      • https://identifiers.org/wikipathways/WP3932_r137139
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      • https://identifiers.org/wikipathways/WP3932_r137139
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    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
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    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
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    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
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    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
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    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
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    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
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    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
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    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
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    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
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    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
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    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
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    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
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    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
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    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
  • https://identifiers.org/ensembl/ENSG00000185236
    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
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    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
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    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
  • https://identifiers.org/ensembl/ENSG00000187840
    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
  • https://identifiers.org/ensembl/ENSG00000196455
    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
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    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
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    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
  • https://identifiers.org/ensembl/ENSG00000196878
    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
  • https://identifiers.org/ensembl/ENSG00000213281
    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
  • https://identifiers.org/ensembl/ENSG00000269335
    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
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    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
  • https://identifiers.org/pubmed/11082269
    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
  • https://identifiers.org/pubmed/14744429
    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
  • https://identifiers.org/ensembl/ENSG00000099617
    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
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    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
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    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
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    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
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    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
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    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
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    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
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    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
  • https://identifiers.org/ensembl/ENSG00000096384
    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
  • https://identifiers.org/ensembl/ENSG00000119535
    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
  • https://identifiers.org/ensembl/ENSG00000119630
    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
  • https://identifiers.org/ensembl/ENSG00000139679
    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
  • https://identifiers.org/ensembl/ENSG00000145431
    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
  • https://identifiers.org/ensembl/ENSG00000147145
    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
  • https://identifiers.org/ensembl/ENSG00000167083
    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
  • https://identifiers.org/ensembl/ENSG00000170962
    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
  • https://identifiers.org/ensembl/ENSG00000171517
    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
  • https://identifiers.org/ensembl/ENSG00000184574
    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
  • https://identifiers.org/ensembl/ENSG00000185291
    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
  • https://identifiers.org/ensembl/ENSG00000187266
    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
  • https://identifiers.org/ensembl/ENSG00000242616
    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
  • https://identifiers.org/ensembl/ENSG00000101280
    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
  • https://identifiers.org/ensembl/ENSG00000118046
    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
  • https://identifiers.org/ensembl/ENSG00000168209
    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
  • https://identifiers.org/ensembl/ENSG00000130635
    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
  • http://rdf.wikipathways.org/Pathway/WP3932_r137139/WP/Interaction/ac6bf
    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
  • http://rdf.wikipathways.org/Pathway/WP3932_r137139/WP/Interaction/d5f2c
    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
  • http://rdf.wikipathways.org/Pathway/WP3932_r137139/WP/Interaction/id4edc8a66
    • http://purl.org/dc/terms/isPartOf
      • https://identifiers.org/wikipathways/WP3932_r137139
  • https://identifiers.org/wikipathways/WP3932_r137139
    • http://www.w3.org/1999/02/22-rdf-syntax-ns#type
      • http://vocabularies.wikipathways.org/wp#Pathway
      • http://www.w3.org/2004/02/skos/core#Collection
    • http://vocabularies.wikipathways.org/wp#isAbout
      • http://rdf.wikipathways.org/Pathway/WP3932_r137139
    • http://vocabularies.wikipathways.org/wp#ontologyTag
      • http://purl.obolibrary.org/obo/PW_0000648
      • http://purl.obolibrary.org/obo/PW_0000003
      • http://vocabularies.wikipathways.org/wp#Curation:CPTAC
      • http://vocabularies.wikipathways.org/wp#Curation:PancCanNet
      • http://vocabularies.wikipathways.org/wp#Curation:ONTOX
      • http://vocabularies.wikipathways.org/wp#Curation:Homology_Converted
      • http://vocabularies.wikipathways.org/wp#Curation:AnalysisCollection
      • http://purl.obolibrary.org/obo/PW_0000180
    • http://vocabularies.wikipathways.org/wp#organism
      • http://purl.obolibrary.org/obo/NCBITaxon_9606
    • http://vocabularies.wikipathways.org/wp#organismName
      • Homo sapiens
    • http://vocabularies.wikipathways.org/wp#pathwayOntologyTag
      • http://purl.obolibrary.org/obo/PW_0000648
      • http://purl.obolibrary.org/obo/PW_0000003
      • http://purl.obolibrary.org/obo/PW_0000180
    • http://xmlns.com/foaf/0.1/img
      • https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=png&pwTitle=Pathway:WP3932&oldid=137139
      • https://www.wikipathways.org//wpi/wpi.php?action=downloadFile&type=svg&pwTitle=Pathway:WP3932&oldid=137139
    • http://xmlns.com/foaf/0.1/page
      • http://www.wikipathways.org/instance/WP3932_r137139
    • http://purl.org/dc/elements/1.1/identifier
      • https://identifiers.org/wikipathways/WP3932
    • http://purl.org/dc/elements/1.1/source
      • WikiPathways
    • http://purl.org/dc/elements/1.1/title
      • Focal adhesion: PI3K-Akt-mTOR-signaling
    • http://purl.org/dc/terms/description
      • Cell-matrix adhesions play important roles in biological processes such as cell motility, cell proliferation, cell differentiation, regulation of gene expression and cell survival. Focal adhesions are structures formed at the cell-extracellular matrix contact points, consisting of bundles of actin filaments anchored to trans-membrane receptors of the integrin family through a complex of multiple proteins. In addition to participating in the structural link between membrane receptors and the actin cytoskeleton, focal adhesions also contain signaling molecules, such as protein kinases and phosphatases, their substrates, and various adapter proteins. Integrin signaling is dependent on the non-receptor tyrosine kinase activities of the FAK and src proteins and the adaptor protein functions of FAK, src and Shc to initiate downstream signaling events. These signaling events results in the reorganization of the actin cytoskeleton, which is essential for changes in cell shape and motility, and gene expression. Source: [KEGG](https://www.genome.jp/dbget-bin/www_bget?pathway+map04510). Proteins on this pathway have targeted assays available via the [CPTAC Assay Portal](https://assays.cancer.gov/available_assays?wp_id=WP3932).
    • http://purl.org/dc/terms/identifier
      • WP3932
    • http://purl.org/dc/terms/references
      • https://identifiers.org/pubmed/11146675
      • https://identifiers.org/pubmed/14756624
      • https://identifiers.org/pubmed/15034601
      • https://identifiers.org/pubmed/15053919
      • https://identifiers.org/pubmed/15108811
      • https://identifiers.org/pubmed/12235283
      • https://identifiers.org/pubmed/12640026
      • https://identifiers.org/pubmed/14519391
      • https://identifiers.org/pubmed/11882383
      • https://identifiers.org/pubmed/11229600
      • https://identifiers.org/pubmed/11573199
      • https://identifiers.org/pubmed/15688067
      • https://identifiers.org/pubmed/15179030
      • https://identifiers.org/pubmed/15459662
      • https://identifiers.org/pubmed/11082269
      • https://identifiers.org/pubmed/14744429
      • https://identifiers.org/pubmed/10698680
    • http://purl.org/spar/cito/cites
      • https://identifiers.org/pubmed/11229600
      • https://identifiers.org/pubmed/11573199
      • https://identifiers.org/pubmed/11882383
      • https://identifiers.org/pubmed/12235283
      • https://identifiers.org/pubmed/12640026
      • https://identifiers.org/pubmed/14519391
      • https://identifiers.org/pubmed/14756624
      • https://identifiers.org/pubmed/15034601
      • https://identifiers.org/pubmed/15053919
      • https://identifiers.org/pubmed/15108811
      • https://identifiers.org/pubmed/11146675
      • https://identifiers.org/pubmed/15179030
      • https://identifiers.org/pubmed/15459662
      • https://identifiers.org/pubmed/15688067
      • https://identifiers.org/pubmed/11082269
      • https://identifiers.org/pubmed/14744429
      • https://identifiers.org/pubmed/10698680