SPARQL | HTML5 RDFa and Microdata document
https://identifiers.org/wikipathways/WP453
https://identifiers.org/ensembl/ENSG00000211890
https://identifiers.org/ensembl/ENSG00000211895
https://identifiers.org/ncbigene/1277
https://identifiers.org/ncbigene/1278
https://identifiers.org/ncbigene/1281
https://identifiers.org/ncbigene/2335
https://identifiers.org/ncbigene/3458
https://identifiers.org/ncbigene/3507
https://identifiers.org/ncbigene/3558
https://identifiers.org/ncbigene/3559
https://identifiers.org/ncbigene/3560
https://identifiers.org/ncbigene/3561
https://identifiers.org/ncbigene/3565
https://identifiers.org/ncbigene/3566
https://identifiers.org/ncbigene/3567
https://identifiers.org/ncbigene/3568
https://identifiers.org/ncbigene/3911
https://identifiers.org/ncbigene/3912
https://identifiers.org/ncbigene/3913
https://identifiers.org/ncbigene/3915
https://identifiers.org/ncbigene/3918
https://identifiers.org/ncbigene/3932
https://identifiers.org/ncbigene/7057
https://identifiers.org/ncbigene/7059
https://identifiers.org/ncbigene/7132
https://identifiers.org/ncbigene/7133
https://identifiers.org/ncbigene/7448
https://identifiers.org/ncbigene/7535
https://identifiers.org/ncbigene/940
https://identifiers.org/ncbigene/941
https://identifiers.org/ncbigene/942
https://identifiers.org/ncbigene/958
https://identifiers.org/ncbigene/959
https://identifiers.org/pubmed/19028820
https://identifiers.org/pubmed/9378992
http://rdf.wikipathways.org/Pathway/WP453_r134674/WP/Interaction/b099a
http://rdf.wikipathways.org/Pathway/WP453_r134674/WP/Interaction/b3333
http://rdf.wikipathways.org/Pathway/WP453_r134674/WP/Interaction/c1df7
http://rdf.wikipathways.org/Pathway/WP453_r134674/WP/Interaction/c6ea5
http://rdf.wikipathways.org/Pathway/WP453_r134674/WP/Interaction/d40e1
http://rdf.wikipathways.org/Pathway/WP453_r134674/WP/Interaction/d6398
http://rdf.wikipathways.org/Pathway/WP453_r134674/WP/Interaction/e00b0
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http://rdf.wikipathways.org/Pathway/WP453_r134674/WP/Interaction/fc8a2
http://rdf.wikipathways.org/Pathway/WP453_r134674/WP/Interaction/ffa39
https://identifiers.org/wikipathways/WP453_r134674
http://www.w3.org/1999/02/22-rdf-syntax-ns#type
http://vocabularies.wikipathways.org/wp#Pathway
http://www.w3.org/2004/02/skos/core#Collection
http://xmlns.com/foaf/0.1/page
http://www.wikipathways.org/instance/WP453_r134674
http://purl.org/dc/elements/1.1/identifier
https://identifiers.org/wikipathways/WP453
http://purl.org/dc/elements/1.1/source
http://purl.org/dc/elements/1.1/title
Inflammatory response pathway
http://purl.org/dc/terms/description
Inflammation is a protective response of cells to pathogens, infection or tissue damage. It involves the coordinated communication of different immune cells and blood vessels through an intricate cascade of molecular signals. Inflammation can cause fever, cardiovascular pathology, allergy anaphylaxis, fibrosis, autoimmunity, etc.
The inflammatory response has four phases: inflammatory inducers (infection or tissue damage), inflammatory sensors (mast cells and macrophages), inflammatory mediators (cytokines, chemokines, etc.) and the tissues that are affected. Each phase has many options that are triggered based on the type pathogen introduced.
In addition, chronic inflammatory conditions, where an inducer is not well defined, are becoming more common. These conditions are of particular interest because they coincide with other diseases such as obesity, type 2 diabetes, atherosclerosis, neurodegenerative diseases and cancer. [http://www.thermofisher.com/ls/en/home/life-science/cell-analysis/signaling-pathways/inflammatory-response-pathway.html#]
Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP453 CPTAC Assay Portal]
http://purl.org/dc/terms/identifier
http://purl.org/dc/terms/references
https://identifiers.org/pubmed/9378992
https://identifiers.org/pubmed/19028820
http://purl.org/spar/cito/cites
https://identifiers.org/pubmed/9378992
https://identifiers.org/pubmed/19028820
http://vocabularies.wikipathways.org/wp#cellTypeOntologyTag
http://purl.obolibrary.org/obo/CL_0000057
http://purl.obolibrary.org/obo/CL_0000492
http://purl.obolibrary.org/obo/CL_0000236
http://purl.obolibrary.org/obo/CL_0000066
http://vocabularies.wikipathways.org/wp#isAbout
http://rdf.wikipathways.org/Pathway/WP453_r134674
http://vocabularies.wikipathways.org/wp#ontologyTag
http://purl.obolibrary.org/obo/PW_0000024
http://purl.obolibrary.org/obo/CL_0000057
http://purl.obolibrary.org/obo/CL_0000492
http://purl.obolibrary.org/obo/CL_0000236
http://purl.obolibrary.org/obo/CL_0000066
http://vocabularies.wikipathways.org/wp#Curation:AnalysisCollection
http://vocabularies.wikipathways.org/wp#organism
http://purl.obolibrary.org/obo/NCBITaxon_9606
http://vocabularies.wikipathways.org/wp#organismName
http://vocabularies.wikipathways.org/wp#pathwayOntologyTag
http://purl.obolibrary.org/obo/PW_0000024
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