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  • http://rdf.wikipathways.org/Pathway/WP5385_r128454/WP/Interaction/id98a5e5f
    • http://purl.org/dc/terms/isPartOf
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    • http://purl.org/dc/terms/isPartOf
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    • http://purl.org/dc/terms/isPartOf
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    • http://purl.org/dc/terms/isPartOf
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      • http://purl.obolibrary.org/obo/CL_0000169
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      • http://purl.obolibrary.org/obo/NCBITaxon_9606
    • http://vocabularies.wikipathways.org/wp#organismName
      • Homo sapiens
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      • WikiPathways
    • http://purl.org/dc/elements/1.1/title
      • Growth factors and hormones in beta cell proliferation
    • http://purl.org/dc/terms/description
      • Growh factors and hormones in Beta-cell proliferation
      • Several growth factors and hormones interact with particular beta-cell receptors to start intracellular signaling pathways that encourage cell division and growth. Hormones including prolactin (PRL), thyroid hormone (TH), growth hormone (GH), glucagon-like peptide-1 (GLP-1), insulin-like growth factor-1 (IGF-1), and others have been closely linked. The modulation of B-cell proliferation has been linked to growth factors such as IGF-1, members of the epidermal growth factor (EGF) family, nerve growth factor (NGF), members of the transforming growth factor (TGF)-superfamily, placental growth factor (PLGF), and their corresponding receptors. This pathway provides information on how these various factors are realized. The figure is based on Jiang et al. (2018, doi: 10.3892/etm.2018.6603).
    • http://purl.org/dc/terms/identifier
      • WP5385
    • http://purl.org/dc/terms/references
      • https://identifiers.org/pubmed/30233674
    • http://purl.org/spar/cito/cites
      • https://identifiers.org/pubmed/30233674
      • https://identifiers.org/pubmed/25133424
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      • https://identifiers.org/pubmed/24639504
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      • https://identifiers.org/pubmed/21993628
      • https://identifiers.org/pubmed/20807437
      • https://identifiers.org/pubmed/17414058